Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors

Three (R)-BINOL-based macrocyclic receptors obtained via double-amidation reaction were used for chiral recognition of four anions derived from α-hydroxy and α-amino acids. The structural factors of hosts and guests that affect chiral recognition processes were also investigated, indicating that the...

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Detalles Bibliográficos
Autores principales: Tyszka-Gumkowska, Agata, Pikus, Grzegorz, Jurczak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680683/
https://www.ncbi.nlm.nih.gov/pubmed/31331097
http://dx.doi.org/10.3390/molecules24142635
Descripción
Sumario:Three (R)-BINOL-based macrocyclic receptors obtained via double-amidation reaction were used for chiral recognition of four anions derived from α-hydroxy and α-amino acids. The structural factors of hosts and guests that affect chiral recognition processes were also investigated, indicating that the proper geometry of both receptor and guest molecules plays a crucial role in effective enantio-discrimination.

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