Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors

Three (R)-BINOL-based macrocyclic receptors obtained via double-amidation reaction were used for chiral recognition of four anions derived from α-hydroxy and α-amino acids. The structural factors of hosts and guests that affect chiral recognition processes were also investigated, indicating that the...

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Autores principales: Tyszka-Gumkowska, Agata, Pikus, Grzegorz, Jurczak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680683/
https://www.ncbi.nlm.nih.gov/pubmed/31331097
http://dx.doi.org/10.3390/molecules24142635
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author Tyszka-Gumkowska, Agata
Pikus, Grzegorz
Jurczak, Janusz
author_facet Tyszka-Gumkowska, Agata
Pikus, Grzegorz
Jurczak, Janusz
author_sort Tyszka-Gumkowska, Agata
collection PubMed
description Three (R)-BINOL-based macrocyclic receptors obtained via double-amidation reaction were used for chiral recognition of four anions derived from α-hydroxy and α-amino acids. The structural factors of hosts and guests that affect chiral recognition processes were also investigated, indicating that the proper geometry of both receptor and guest molecules plays a crucial role in effective enantio-discrimination.
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spelling pubmed-66806832019-08-09 Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors Tyszka-Gumkowska, Agata Pikus, Grzegorz Jurczak, Janusz Molecules Article Three (R)-BINOL-based macrocyclic receptors obtained via double-amidation reaction were used for chiral recognition of four anions derived from α-hydroxy and α-amino acids. The structural factors of hosts and guests that affect chiral recognition processes were also investigated, indicating that the proper geometry of both receptor and guest molecules plays a crucial role in effective enantio-discrimination. MDPI 2019-07-19 /pmc/articles/PMC6680683/ /pubmed/31331097 http://dx.doi.org/10.3390/molecules24142635 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tyszka-Gumkowska, Agata
Pikus, Grzegorz
Jurczak, Janusz
Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors
title Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors
title_full Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors
title_fullStr Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors
title_full_unstemmed Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors
title_short Chiral Recognition of Carboxylate Anions by (R)-BINOL-Based Macrocyclic Receptors
title_sort chiral recognition of carboxylate anions by (r)-binol-based macrocyclic receptors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680683/
https://www.ncbi.nlm.nih.gov/pubmed/31331097
http://dx.doi.org/10.3390/molecules24142635
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AT pikusgrzegorz chiralrecognitionofcarboxylateanionsbyrbinolbasedmacrocyclicreceptors
AT jurczakjanusz chiralrecognitionofcarboxylateanionsbyrbinolbasedmacrocyclicreceptors

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