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Characterization of a Reservoir-Style Implant for Sustained Release of Tenofovir Alafenamide (TAF) for HIV Pre-Exposure Prophylaxis (PrEP)

Long-acting (LA) HIV pre-exposure prophylaxis (PrEP) offers the potential to improve adherence by lowering the burden of daily or on-demand regimens of antiretroviral (ARV) drugs. This paper details the fabrication and in vitro performance of a subcutaneous and trocar-compatible implant for the LA d...

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Detalles Bibliográficos
Autores principales: Johnson, Leah M., Krovi, Sai Archana, Li, Linying, Girouard, Natalie, Demkovich, Zach R., Myers, Daniel, Creelman, Ben, van der Straten, Ariane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680758/
https://www.ncbi.nlm.nih.gov/pubmed/31277461
http://dx.doi.org/10.3390/pharmaceutics11070315