Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Gastrin-releasing peptide receptor (GRPR) and prostate-specific membrane antigen (PSMA) are overexpressed in most prostate cancers. GRPR expression is higher in early stages while PSMA expression increases with progression. The possibility of targeting both markers with a single theranostics radiotr...

Descripción completa

Detalles Bibliográficos
Autores principales: Abouzayed, Ayman, Yim, Cheng-Bin, Mitran, Bogdan, Rinne, Sara S., Tolmachev, Vladimir, Larhed, Mats, Rosenström, Ulrika, Orlova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680768/
https://www.ncbi.nlm.nih.gov/pubmed/31340483
http://dx.doi.org/10.3390/pharmaceutics11070358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680768/
https://www.ncbi.nlm.nih.gov/pubmed/31340483
http://dx.doi.org/10.3390/pharmaceutics11070358

Ejemplares similares