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Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer

Gastrin-releasing peptide receptor (GRPR) and prostate-specific membrane antigen (PSMA) are overexpressed in most prostate cancers. GRPR expression is higher in early stages while PSMA expression increases with progression. The possibility of targeting both markers with a single theranostics radiotr...

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Detalles Bibliográficos
Autores principales:	Abouzayed, Ayman, Yim, Cheng-Bin, Mitran, Bogdan, Rinne, Sara S., Tolmachev, Vladimir, Larhed, Mats, Rosenström, Ulrika, Orlova, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680768/ https://www.ncbi.nlm.nih.gov/pubmed/31340483 http://dx.doi.org/10.3390/pharmaceutics11070358

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