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(1)H HR-MAS NMR-Based Metabolomics of Cancer Cells in Response to Treatment with the Diruthenium Trithiolato Complex [(p-MeC(6)H(4)(i)Pr)(2)Ru(2)(SC(6)H(4)-p-Bu(t))(3)](+) (DiRu-1)
The trithiolato bridged diruthenium complex DiRu-1 [(p-MeC(6)H(4)(i)Pr)(2)Ru(2)(SC(6)H(4)-p-Bu(t))(3)](+) is highly cytotoxic against various cancer cell lines, but its exact mode of action remains unknown. The present (1)H HR-MAS NMR-based metabolomic study was performed on ovarian cancer cell line...
Autores principales: | Primasová, Hedvika, Paul, Lydia E. H., Diserens, Gaëlle, Primasová, Ester, Vermathen, Peter, Vermathen, Martina, Furrer, Julien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680816/ https://www.ncbi.nlm.nih.gov/pubmed/31323867 http://dx.doi.org/10.3390/metabo9070146 |
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