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Biological Obstacles for Identifying In Vitro-In Vivo Correlations of Orally Inhaled Formulations
Oral inhalation of drugs is the classic therapy of obstructive lung diseases. In contrast to the oral route, the link between in vitro and in vivo findings is less well defined and predictive models and parameters for in vitro-in vivo correlations are missing. Frequently used in vitro models and pro...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680885/ https://www.ncbi.nlm.nih.gov/pubmed/31284402 http://dx.doi.org/10.3390/pharmaceutics11070316 |