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The Preparation of Green Fluorescence-Emissioned Carbon Dots/Poly(N-Isopropylacrylamide) Temperature-Sensitive Hydrogels and Research on Their Properties

Fluorescence/temperature-sensitive hydrogels, thanks to their properties in fluorescence and temperature sensitivity, have shown a promising outlook in the fields of drug delivery, cell imaging, etc., and thus become the focus of present research. This paper reports the preparation of green-fluoresc...

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Detalles Bibliográficos
Autores principales: Zhao, Dan, Ma, Wenting, Wang, Rong, Yang, Xinzhou, Li, Jun, Qiu, Ting, Xiao, Xincai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680904/
https://www.ncbi.nlm.nih.gov/pubmed/31373306
http://dx.doi.org/10.3390/polym11071171
Descripción
Sumario:Fluorescence/temperature-sensitive hydrogels, thanks to their properties in fluorescence and temperature sensitivity, have shown a promising outlook in the fields of drug delivery, cell imaging, etc., and thus become the focus of present research. This paper reports the preparation of green-fluorescence/temperature-sensitive hydrogels through one-step radical polymerization with green fluorescence-emissioned carbon dots as fluorescence probes and N-isopropylacrylamide as a monomer. UV-vis spectra, fluorescence spectra, and fluorescence microscope imaging have been used to characterize the prepared hydrogel, and to study their optical and temperature-sensitive properties. It was discovered that the emission of prepared hydrogel is excitation wavelength-dependent, pH responding, and excellent temperature-sensitive, as well as having good biocompatibility. The prepared hydrogel can also be applied as fluorescence ink in the fields of anti-counterfeit identification and appraisal.