Design, Synthesis, and Biological Evaluation of EdAP, a 4′-Ethynyl-2′-Deoxyadenosine 5′-Monophosphate Analog, as a Potent Influenza a Inhibitor

Influenza A viruses leading to infectious respiratory diseases cause seasonal epidemics and sometimes periodic global pandemics. Viral polymerase is an attractive target in inhibiting viral replication, and 4′-ethynyladenosine, which has been reported as a highly potent anti-human immunodeficiency v...

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Detalles Bibliográficos
Autores principales: Takeuchi, Toshifumi, Sriwilaijaroen, Nongluk, Sakuraba, Ayako, Hayashi, Ei, Kamisuki, Shinji, Suzuki, Yasuo, Ohrui, Hiroshi, Sugawara, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681032/
https://www.ncbi.nlm.nih.gov/pubmed/31319565
http://dx.doi.org/10.3390/molecules24142603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681032/
https://www.ncbi.nlm.nih.gov/pubmed/31319565
http://dx.doi.org/10.3390/molecules24142603

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