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Antioxidant and Anti-Inflammatory Properties of Mastiha: A Review of Preclinical and Clinical Studies

Nowadays both scientists and consumers have an increasing interest for natural products as preventing and healing factors without side effects. Mastiha, is a natural product of the Mediterranean basin with several health benefits as investigated the last decades. The present review summarises the re...

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Detalles Bibliográficos
Autores principales: Papada, Efstathia, Kaliora, Andriana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681034/
https://www.ncbi.nlm.nih.gov/pubmed/31284520
http://dx.doi.org/10.3390/antiox8070208
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author Papada, Efstathia
Kaliora, Andriana C.
author_facet Papada, Efstathia
Kaliora, Andriana C.
author_sort Papada, Efstathia
collection PubMed
description Nowadays both scientists and consumers have an increasing interest for natural products as preventing and healing factors without side effects. Mastiha, is a natural product of the Mediterranean basin with several health benefits as investigated the last decades. The present review summarises the research evidence from preclinical and clinical studies regarding the antioxidant and anti-inflammatory potential of Mastiha. MEDLINE, COHRANE and search terms “Mastiha”, “Mastic gum”, “Chios mastic” and “Pistacia lentiscus” were used. We limited our search by selecting only articles written in English literature, published between 2003 and 2019 that were experimental studies on Mastiha resinous exudate (review articles and individual case reports were excluded). Additional searches were performed using “oxidative stress” and “inflammation”. A total of 19 studies met our criteria and were included in this review. Currently, there are more preclinical than clinical data available. Taken all together, the antioxidant potential of Mastiha is most probably owed to the inhibition of protein kinase, while its anti-inflammatory capacity may be the result of the inhibition of NF-κB activation. Further clinical studies in large populations are necessary.
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spelling pubmed-66810342019-08-09 Antioxidant and Anti-Inflammatory Properties of Mastiha: A Review of Preclinical and Clinical Studies Papada, Efstathia Kaliora, Andriana C. Antioxidants (Basel) Review Nowadays both scientists and consumers have an increasing interest for natural products as preventing and healing factors without side effects. Mastiha, is a natural product of the Mediterranean basin with several health benefits as investigated the last decades. The present review summarises the research evidence from preclinical and clinical studies regarding the antioxidant and anti-inflammatory potential of Mastiha. MEDLINE, COHRANE and search terms “Mastiha”, “Mastic gum”, “Chios mastic” and “Pistacia lentiscus” were used. We limited our search by selecting only articles written in English literature, published between 2003 and 2019 that were experimental studies on Mastiha resinous exudate (review articles and individual case reports were excluded). Additional searches were performed using “oxidative stress” and “inflammation”. A total of 19 studies met our criteria and were included in this review. Currently, there are more preclinical than clinical data available. Taken all together, the antioxidant potential of Mastiha is most probably owed to the inhibition of protein kinase, while its anti-inflammatory capacity may be the result of the inhibition of NF-κB activation. Further clinical studies in large populations are necessary. MDPI 2019-07-05 /pmc/articles/PMC6681034/ /pubmed/31284520 http://dx.doi.org/10.3390/antiox8070208 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Papada, Efstathia
Kaliora, Andriana C.
Antioxidant and Anti-Inflammatory Properties of Mastiha: A Review of Preclinical and Clinical Studies
title Antioxidant and Anti-Inflammatory Properties of Mastiha: A Review of Preclinical and Clinical Studies
title_full Antioxidant and Anti-Inflammatory Properties of Mastiha: A Review of Preclinical and Clinical Studies
title_fullStr Antioxidant and Anti-Inflammatory Properties of Mastiha: A Review of Preclinical and Clinical Studies
title_full_unstemmed Antioxidant and Anti-Inflammatory Properties of Mastiha: A Review of Preclinical and Clinical Studies
title_short Antioxidant and Anti-Inflammatory Properties of Mastiha: A Review of Preclinical and Clinical Studies
title_sort antioxidant and anti-inflammatory properties of mastiha: a review of preclinical and clinical studies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681034/
https://www.ncbi.nlm.nih.gov/pubmed/31284520
http://dx.doi.org/10.3390/antiox8070208
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