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CK‐2127107 amplifies skeletal muscle response to nerve activation in humans

Introduction Three studies evaluated safety, tolerability, pharmacokinetics, and pharmacodynamics of CK‐2127107 (CK‐107), a next‐generation fast skeletal muscle troponin activator (FSTA), in healthy participants. We tested the hypothesis that CK‐107 would amplify the force‐frequency response of musc...

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Detalles Bibliográficos
Autores principales:	Andrews, Jinsy A., Miller, Timothy M., Vijayakumar, Vipin, Stoltz, Randall, James, Joyce K., Meng, Lisa, Wolff, Andrew A., Malik, Fady I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681065/ https://www.ncbi.nlm.nih.gov/pubmed/29150952 http://dx.doi.org/10.1002/mus.26017

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