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Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma
The optimal therapy for advanced thymic carcinoma has long been controversial. Despite that complete (R0) resection is recommend as the first-line treatment, multidisciplinary approach including chemotherapy and radiotherapy should be considered for patients who lost the operation chance or received...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681131/ https://www.ncbi.nlm.nih.gov/pubmed/31374122 http://dx.doi.org/10.1093/omcr/omz070 |
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author | Han, Ling Zhang, Baozhu Wu, Shihai |
author_facet | Han, Ling Zhang, Baozhu Wu, Shihai |
author_sort | Han, Ling |
collection | PubMed |
description | The optimal therapy for advanced thymic carcinoma has long been controversial. Despite that complete (R0) resection is recommend as the first-line treatment, multidisciplinary approach including chemotherapy and radiotherapy should be considered for patients who lost the operation chance or received incomplete resection. Here, we present a case who received concurrent chemoradiotherapy (CCRT) after cytoreductive surgery. A complete response was observed and the patient has remained disease free for over 4 years. To our knowledge, this is the first report to demonstrate the efficacy of CCRT with cisplatin plus etoposide after incomplete surgery for advanced thymic carcinoma. |
format | Online Article Text |
id | pubmed-6681131 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-66811312019-08-07 Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma Han, Ling Zhang, Baozhu Wu, Shihai Oxf Med Case Reports Case Report The optimal therapy for advanced thymic carcinoma has long been controversial. Despite that complete (R0) resection is recommend as the first-line treatment, multidisciplinary approach including chemotherapy and radiotherapy should be considered for patients who lost the operation chance or received incomplete resection. Here, we present a case who received concurrent chemoradiotherapy (CCRT) after cytoreductive surgery. A complete response was observed and the patient has remained disease free for over 4 years. To our knowledge, this is the first report to demonstrate the efficacy of CCRT with cisplatin plus etoposide after incomplete surgery for advanced thymic carcinoma. Oxford University Press 2019-08-02 /pmc/articles/PMC6681131/ /pubmed/31374122 http://dx.doi.org/10.1093/omcr/omz070 Text en © The Author(s) 2019. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Han, Ling Zhang, Baozhu Wu, Shihai Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma |
title | Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma |
title_full | Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma |
title_fullStr | Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma |
title_full_unstemmed | Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma |
title_short | Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma |
title_sort | successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681131/ https://www.ncbi.nlm.nih.gov/pubmed/31374122 http://dx.doi.org/10.1093/omcr/omz070 |
work_keys_str_mv | AT hanling successfulconcurrentchemoradiotherapywithcisplatinplusetoposideafterincompleteresectionforadvancedthymiccarcinoma AT zhangbaozhu successfulconcurrentchemoradiotherapywithcisplatinplusetoposideafterincompleteresectionforadvancedthymiccarcinoma AT wushihai successfulconcurrentchemoradiotherapywithcisplatinplusetoposideafterincompleteresectionforadvancedthymiccarcinoma |