Cargando…

Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma

The optimal therapy for advanced thymic carcinoma has long been controversial. Despite that complete (R0) resection is recommend as the first-line treatment, multidisciplinary approach including chemotherapy and radiotherapy should be considered for patients who lost the operation chance or received...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Ling, Zhang, Baozhu, Wu, Shihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681131/
https://www.ncbi.nlm.nih.gov/pubmed/31374122
http://dx.doi.org/10.1093/omcr/omz070
_version_ 1783441661474373632
author Han, Ling
Zhang, Baozhu
Wu, Shihai
author_facet Han, Ling
Zhang, Baozhu
Wu, Shihai
author_sort Han, Ling
collection PubMed
description The optimal therapy for advanced thymic carcinoma has long been controversial. Despite that complete (R0) resection is recommend as the first-line treatment, multidisciplinary approach including chemotherapy and radiotherapy should be considered for patients who lost the operation chance or received incomplete resection. Here, we present a case who received concurrent chemoradiotherapy (CCRT) after cytoreductive surgery. A complete response was observed and the patient has remained disease free for over 4 years. To our knowledge, this is the first report to demonstrate the efficacy of CCRT with cisplatin plus etoposide after incomplete surgery for advanced thymic carcinoma.
format Online
Article
Text
id pubmed-6681131
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-66811312019-08-07 Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma Han, Ling Zhang, Baozhu Wu, Shihai Oxf Med Case Reports Case Report The optimal therapy for advanced thymic carcinoma has long been controversial. Despite that complete (R0) resection is recommend as the first-line treatment, multidisciplinary approach including chemotherapy and radiotherapy should be considered for patients who lost the operation chance or received incomplete resection. Here, we present a case who received concurrent chemoradiotherapy (CCRT) after cytoreductive surgery. A complete response was observed and the patient has remained disease free for over 4 years. To our knowledge, this is the first report to demonstrate the efficacy of CCRT with cisplatin plus etoposide after incomplete surgery for advanced thymic carcinoma. Oxford University Press 2019-08-02 /pmc/articles/PMC6681131/ /pubmed/31374122 http://dx.doi.org/10.1093/omcr/omz070 Text en © The Author(s) 2019. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Han, Ling
Zhang, Baozhu
Wu, Shihai
Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma
title Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma
title_full Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma
title_fullStr Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma
title_full_unstemmed Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma
title_short Successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma
title_sort successful concurrent chemoradiotherapy with cisplatin plus etoposide after incomplete resection for advanced thymic carcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681131/
https://www.ncbi.nlm.nih.gov/pubmed/31374122
http://dx.doi.org/10.1093/omcr/omz070
work_keys_str_mv AT hanling successfulconcurrentchemoradiotherapywithcisplatinplusetoposideafterincompleteresectionforadvancedthymiccarcinoma
AT zhangbaozhu successfulconcurrentchemoradiotherapywithcisplatinplusetoposideafterincompleteresectionforadvancedthymiccarcinoma
AT wushihai successfulconcurrentchemoradiotherapywithcisplatinplusetoposideafterincompleteresectionforadvancedthymiccarcinoma