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Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy

Despite genetic heterogeneity, early manifestation of diastolic dysfunction (DD) is common in hypertrophic cardiomyopathy (HCM). Nitric oxide (NO) may contribute to myocardial relaxation. NO synthases (NOS) use l-arginine (Arg) as a substrate, as asymmetric dimethylarginine (ADMA) is a direct endoge...

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Detalles Bibliográficos
Autores principales: Cordts, Kathrin, Seelig, Doreen, Lund, Natalie, Carrier, Lucie, Böger, Rainer H., Avanesov, Maxim, Tahir, Enver, Schwedhelm, Edzard, Patten, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681289/
https://www.ncbi.nlm.nih.gov/pubmed/31337005
http://dx.doi.org/10.3390/biom9070277