Formononetin Regulates Multiple Oncogenic Signaling Cascades and Enhances Sensitivity to Bortezomib in a Multiple Myeloma Mouse Model

Here, we determined the anti-neoplastic actions of formononetin (FT) against multiple myeloma (MM) and elucidated its possible mode of action. It was observed that FT enhanced the apoptosis caused by bortezomib (Bor) and mitigated proliferation in MM cells, and these events are regulated by nuclear...

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Autores principales: Kim, Chulwon, Lee, Jong Hyun, Ko, Jeong-Hyeon, Chinnathambi, Arunachalam, Alharbi, Sulaiman Ali, Shair, Omar H.M., Sethi, Gautam, Ahn, Kwang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681380/
https://www.ncbi.nlm.nih.gov/pubmed/31284669
http://dx.doi.org/10.3390/biom9070262

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