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Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis
Clinical and experimental studies have shown that opisthorchii tend to evade tumour growth foci to colonize more distant areas of the liver. When modelling tumours with various carcinogens in the setting of superinvasive opisthorchiasis, the intensity of invasion is reduced both before the formation...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681594/ https://www.ncbi.nlm.nih.gov/pubmed/31428553 http://dx.doi.org/10.1155/2019/8079368 |
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author | Bychkov, Vitaly G. Kalyonova, Ludmila F. Khadieva, Elena D. Lazarev, Semen D. Lukmanov, Ilgiz R. Shidin, Vladimir A. Morozov, Evgeny N. |
author_facet | Bychkov, Vitaly G. Kalyonova, Ludmila F. Khadieva, Elena D. Lazarev, Semen D. Lukmanov, Ilgiz R. Shidin, Vladimir A. Morozov, Evgeny N. |
author_sort | Bychkov, Vitaly G. |
collection | PubMed |
description | Clinical and experimental studies have shown that opisthorchii tend to evade tumour growth foci to colonize more distant areas of the liver. When modelling tumours with various carcinogens in the setting of superinvasive opisthorchiasis, the intensity of invasion is reduced both before the formation of neoplasms (>120 days) and after the development of tumours of various histogeneses (liver, pancreas, and stomach) (>240 days). Egg production was observed to increase with the decrease in the number of parasites in the liver. The smallest changes in the infestation intensity indicators and egg production were observed in the experimental stomach tumours (p > 0.05). A partial hepatectomy in the setting of opisthorchiasis did not affect the number of parasites in the ecological niche (liver) or the production of eggs by the helminth. With the deterioration of the vegetation state, parasite clumps of opisthorchii increase egg production under the conditions of distress. |
format | Online Article Text |
id | pubmed-6681594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-66815942019-08-19 Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis Bychkov, Vitaly G. Kalyonova, Ludmila F. Khadieva, Elena D. Lazarev, Semen D. Lukmanov, Ilgiz R. Shidin, Vladimir A. Morozov, Evgeny N. Anal Cell Pathol (Amst) Research Article Clinical and experimental studies have shown that opisthorchii tend to evade tumour growth foci to colonize more distant areas of the liver. When modelling tumours with various carcinogens in the setting of superinvasive opisthorchiasis, the intensity of invasion is reduced both before the formation of neoplasms (>120 days) and after the development of tumours of various histogeneses (liver, pancreas, and stomach) (>240 days). Egg production was observed to increase with the decrease in the number of parasites in the liver. The smallest changes in the infestation intensity indicators and egg production were observed in the experimental stomach tumours (p > 0.05). A partial hepatectomy in the setting of opisthorchiasis did not affect the number of parasites in the ecological niche (liver) or the production of eggs by the helminth. With the deterioration of the vegetation state, parasite clumps of opisthorchii increase egg production under the conditions of distress. Hindawi 2019-07-24 /pmc/articles/PMC6681594/ /pubmed/31428553 http://dx.doi.org/10.1155/2019/8079368 Text en Copyright © 2019 Vitaly G. Bychkov et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Bychkov, Vitaly G. Kalyonova, Ludmila F. Khadieva, Elena D. Lazarev, Semen D. Lukmanov, Ilgiz R. Shidin, Vladimir A. Morozov, Evgeny N. Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
title | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
title_full | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
title_fullStr | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
title_full_unstemmed | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
title_short | Dynamics of the O. felineus Infestation Intensity and Egg Production in Carcinogenesis and Partial Hepatectomy in the Setting of Superinvasive Opisthorchiasis |
title_sort | dynamics of the o. felineus infestation intensity and egg production in carcinogenesis and partial hepatectomy in the setting of superinvasive opisthorchiasis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681594/ https://www.ncbi.nlm.nih.gov/pubmed/31428553 http://dx.doi.org/10.1155/2019/8079368 |
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