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Bone Marrow-Derived CD44(+) Cells Migrate to Tissue-Engineered Constructs via SDF-1/CXCR4-JNK Pathway and Aid Bone Repair

BACKGROUND AND AIMS: Host-derived cells play crucial roles in the regeneration process of tissue-engineered constructs (TECs) during the treatment of large segmental bone defects (LSBDs). However, their identity, source, and cell recruitment mechanisms remain elusive. METHODS: A complex model was cr...

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Detalles Bibliográficos
Autores principales:	Lu, Yanzhu, Xing, Junchao, Yin, Xiaolong, Zhu, Xiaobo, Yang, Aijun, Luo, Jiyue, Gou, Jing, Dong, Shiwu, Xu, Jianzhong, Hou, Tianyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681616/ https://www.ncbi.nlm.nih.gov/pubmed/31428156 http://dx.doi.org/10.1155/2019/1513526

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