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Investigating the Deoxyribonuclease Activity of CRM197 with Site-Directed Mutagenesis
[Image: see text] The protein cross-reactive material 197 (CRM197) is known to catalyze the hydrolytic cleavage of DNA (DNase activity). A suspected metal-binding site (S109, T111, and E112) and suspected DNA-binding motif (T89, K90, and V91) were predicted within the CRM197 protein X-ray crystal st...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682014/ https://www.ncbi.nlm.nih.gov/pubmed/31460310 http://dx.doi.org/10.1021/acsomega.9b00418 |