Cargando…

Small-Intestine-Specific Delivery of Antidiabetic Extracts from Withania coagulans Using Polysaccharide-Based Enteric-Coated Nanoparticles

[Image: see text] Withania coagulans is an Indian medicinal herb, the natural extracts of which are purported to have health-benefiting properties. In this study, the extract was encapsulated in nature-derived polymers with the aim of enhancing its bioavailability. The aqueous extract obtained from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sampathkumar, Kaarunya, Riyajan, Siriporn, Tan, Chiew Kei, Demokritou, Philip, Chudapongse, Nuannoi, Loo, Say Chye Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682046/ https://www.ncbi.nlm.nih.gov/pubmed/31460318 http://dx.doi.org/10.1021/acsomega.9b00823

Ejemplares similares

Antidiabetic activity, glucose uptake stimulation and α-glucosidase inhibitory effect of Chrysophyllum cainito L. stem bark extract
por: Doan, Hau Van, et al.
Publicado: (2018)

Developing Nano-Delivery Systems for Agriculture and Food Applications with Nature-Derived Polymers
por: Sampathkumar, Kaarunya, et al.
Publicado: (2020)

Withania Coagulans and Somnifera
por: Verghese, M.
Publicado: (1885)

Isolation of Antidiabetic Withanolides from Withania coagulans Dunal and Their In Vitro and In Silico Validation
por: Maher, Saima, et al.
Publicado: (2020)

Evaluation of the Antidiabetic Potential of an Isolated Hydroalcoholic Fraction from the Fruit of Withania coagulans
por: Waris, Md., et al.
Publicado: (2021)

Antioxidant, α-glucosidase inhibitory activity and sub-chronic toxicity of Derris reticulata extract: its antidiabetic potential
por: Kumkrai, Pakarang, et al.
Publicado: (2015)

Antidiabetic and antihyperlipidemic activity of hydroalcoholic extract of Withania coagulans Dunal dried fruit in experimental rat models
por: Datta, Ankur, et al.
Publicado: (2013)

Antiproliferative and Antioxidant Effects of Withania coagulans Extract on Benign Prostatic Hyperplasia in Rats
por: Sarbishegi, Maryam, et al.
Publicado: (2016)

Protective Effect of Withania coagulans Fruit Extract on Cisplatin-induced Nephrotoxicity in Rats
por: Sharma, Sonam, et al.
Publicado: (2017)

The effects of camel chymosin and Withania coagulans extract on camel and bovine milk cheeses
por: Mbye, Mustapha, et al.
Publicado: (2021)

Fractionation of Biomolecules in Withania coagulans Extract for Bioreductive Nanoparticle Synthesis, Antifungal and Biofilm Activity
por: Hasan, Murtaza, et al.
Publicado: (2020)

Phytochemistry, Food Application, and Therapeutic Potential of the Medicinal Plant (Withania coagulans): A Review
por: Khan, Muhammad Issa, et al.
Publicado: (2021)

Therapeutic lipid-coated hybrid nanoparticles against bacterial infections
por: Jiang, Lai, et al.
Publicado: (2020)

Lipid-Coated Hybrid Nanoparticles for Enhanced Bacterial Biofilm Penetration and Antibiofilm Efficacy
por: Lee, Hiang Wee, et al.
Publicado: (2022)

A clinical study on the effect of Rishyagandha (Withania coagulans) in the management of Prameha (Type II Diabetes Mellitus)
por: Upadhyay, B. N., et al.
Publicado: (2011)

Withania coagulans Fruit Extract Reduces Oxidative Stress and Inflammation in Kidneys of Streptozotocin-Induced Diabetic Rats
por: Ojha, Shreesh, et al.
Publicado: (2014)

Neuroprotective effects of Withania coagulans root extract on CA1 hippocampus following cerebral ischemia in rats
por: Sarbishegi, Maryam, et al.
Publicado: (2016)

Preparation, Characterization of Pregabalin and Withania coagulans Extract-Loaded Topical Gel and Their Comparative Effect on Burn Injury
por: Asghar, Anam, et al.
Publicado: (2022)

Agrobacterium-Mediated Genetic Transformation of Withania coagulans (Dunal) with rol A Genes and Its Antioxidant Potential
por: Rehman, Samiya, et al.
Publicado: (2023)

Chrysophyllum cainito stem bark extract induces apoptosis in Human hepatocarcinoma HepG2 cells through ROS-mediated mitochondrial pathway
por: Doan, Hau V., et al.
Publicado: (2020)

Evaluation of apoptotic activity of Withania coagulans methanolic extract against human breast cancer and Vero cell lines
por: Ahmad, Rumana, et al.
Publicado: (2017)

In Silico Characterization of Withania coagulans Bioactive Compounds as Potential Inhibitors of Hydroxymethylglutaryl (HMG-CoA) Reductase of Mus musculus
por: Azmi, Muhammad Bilal, et al.
Publicado: (2023)

Valorizing okara waste into nutritionally rich polysaccharide/protein-extracts for co-encapsulation of β-carotene and ferrous sulphate as a potential approach to tackle micronutrient malnutrition
por: Kharel, Sharad, et al.
Publicado: (2021)

Streptomyces chiangmaiensis SSUT88A mediated green synthesis of silver nanoparticles: characterization and evaluation of antibacterial action against clinical drug-resistant strains
por: Rosyidah, A'liyatur, et al.
Publicado: (2022)

Modulating Drug Release from Gastric-Floating Microcapsules through Spray-Coating Layers
por: Lee, Wei Li, et al.
Publicado: (2014)

Prospects of kefiran as a food-derived biopolymer for agri-food and biomedical applications
por: Tan, Kei-Xian, et al.
Publicado: (2020)

Withania coagulans Extract Induces Cell Apoptosis and Inhibits COX-2 Expression in a Rat Model of Benign Prostatic Hyperplasia
por: Sarbishegi, Maryam, et al.
Publicado: (2016)

Antibacterial activity of Aquilaria crassna leaf extract against Staphylococcus epidermidis by disruption of cell wall
por: Kamonwannasit, Sirilak, et al.
Publicado: (2013)

Formulation Development of a Food-Graded Curcumin-Loaded Medium Chain Triglycerides-Encapsulated Kappa Carrageenan (CUR-MCT-KC) Gel Bead Based Oral Delivery Formulation
por: Tan, Kei-Xian, et al.
Publicado: (2021)

Intelligent Nanoparticle-Based Dressings for Bacterial Wound Infections
por: Jiang, Lai, et al.
Publicado: (2020)

Short term UV-B radiation mediated modulation of physiological traits and withanolides production in Withania coagulans (L.) Dunal under in-vitro condition
por: Tripathi, Deepika, et al.
Publicado: (2021)

Potential Probiotic Strains From Milk and Water Kefir Grains in Singapore—Use for Defense Against Enteric Bacterial Pathogens
por: Tan, Li Ling, et al.
Publicado: (2022)

In vitro anticancer activities of Withania coagulans against HeLa, MCF-7, RD, RG2, and INS-1 cancer cells and phytochemical analysis
por: Maqsood, Muhammad, et al.
Publicado: (2018)

Fabrication of Piezoelectric Electrospun Termite Nest-like 3D Scaffolds for Tissue Engineering
por: Muenwacha, Thanapon, et al.
Publicado: (2021)

Improvements in HOMA indices and pancreatic endocrinal tissues in type 2-diabetic rats by DPP-4 inhibition and antioxidant potential of an ethanol fruit extract of Withania coagulans
por: Ram, Heera, et al.
Publicado: (2021)

Cellulose Nanofiber Platform for Pesticide Sequestration in the Gastrointestinal Tract
por: Ho, Chin Guan, et al.
Publicado: (2023)

Co-Combination of Pregabalin and Withania coagulans-Extract-Loaded Topical Gel Alleviates Allodynia and Hyperalgesia in the Chronic Sciatic Nerve Constriction Injury for Neuropathic Pain in Animal Model
por: Asghar, Anam, et al.
Publicado: (2022)

Melatonin Confers NaCl Tolerance in Withania coagulans L. by Maintaining Na(+)/K(+) Homeostasis, Strengthening the Antioxidant Defense System and Modulating Withanolides Synthesis-Related Genes
por: Dehvari-Nagan, P., et al.
Publicado: (2023)

Alginate encapsulation improves probiotics survival in carbonated sodas and beers
por: Tan, Li Ling, et al.
Publicado: (2023)

In Vitro Alpha-Amylase and Alpha-Glucosidase Inhibitory Activity and In Vivo Antidiabetic Activity of Withania frutescens L. Foliar Extract
por: Mechchate, Hamza, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2oo2s9kkb0em6iuh22fsh61cra