Macromolecular Probe Based on a Ni(II)/Tb(III) Coordination Polymer for Sensitive Recognition of Human Serum Albumin (HSA) and MnO(4)(–)

[Image: see text] Reported here are the design and fluorescence characters of a Ni(II)/Tb(III) polymer, [Tb(2)Ni(3)(HCAM)(6)(H(2)O)(12)](n) (1) (H(3)CAM = chelidamic acid). Under physiological conditions, the binding of biocompatible water soluble 1 to human serum albumin (HSA) was studied by spectroscopy techniques, which revealed that 1 could inherent the fluorescent light of HSA in a static quencher course and change the HSA second-level structure. The marked enhancement in 1 and its fluorescence intensity provide conclusive evidence that 1 can play the role of a “turn-on” sensor for recognition and detection of HSA in other biological interferents with a K(sv) value of 7.68 × 10(4) M(–1) and a detection limit of 0.14 μM. Luminescence experiments show that 1 has high selectivity and sensitivity to MnO(4)(–) in other anions. Its quenching efficiency (K(sv)) is 5.54 × 10(3) M(–1), and the detection limit is 0.29 μM.