Electrostatic complex of neurotrophin 4 with dendrimer nanoparticles: controlled release of protein in vitro and in vivo

Background: NT4 has been regarded as a promising therapeutic protein for treatment of damaged retinal pigment epithelium cells. Purpose: Here, we studied physicochemical parameters of an NT4–polyamidoamine (PAMAM) electrostatic complex, which can provide a sustained concentration of protein in intra...

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Detalles Bibliográficos
Autores principales: Dąbkowska, Maria, Rogińska, Dorota, Kłos, Patrycja, Sobuś, Anna, Adamczak, Małgorzata, Litwińska, Zofia, Machalińska, Anna, Machaliński, Bogusław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682179/
https://www.ncbi.nlm.nih.gov/pubmed/31534337
http://dx.doi.org/10.2147/IJN.S210140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682179/
https://www.ncbi.nlm.nih.gov/pubmed/31534337
http://dx.doi.org/10.2147/IJN.S210140

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