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Prognostic significance of human telomerase reverse transcriptase promoter region mutations C228T and C250T for overall survival in spinal chordomas

BACKGROUND: Spinal chordomas, a subtype of primary spinal column malignancies (PSCM), are rare tumors with poor prognosis, and we have limited understanding of the molecular drivers of neoplasia. METHODS: Study design was a retrospective review of prospectively collected data with cross-sectional su...

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Detalles Bibliográficos
Autores principales:	Bettegowda, Chetan, Yip, Stephen, Jiang, Bowen, Wang, Wei-Lien, Clarke, Michelle J, Lazary, Aron, Gambarotti, Marco, Zhang, Ming, Sciubba, Daniel M, Wolinsky, Jean-Paul, Goodwin, C Rory, McCarthy, Edward, Germscheid, Niccole M, Sahgal, Arjun, Gokaslan, Ziya L, Boriani, Stefano, Varga, Peter Pal, Fisher, Charles G, Rhines, Laurence D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682209/ https://www.ncbi.nlm.nih.gov/pubmed/30976795 http://dx.doi.org/10.1093/neuonc/noz066

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