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A cell-engineered system to assess tumor cell sensitivity to CD8(+) T cell-mediated cytotoxicity

In vitro assays that evaluate CD8(+) T cell-mediated cytotoxicity are important to aid in the development of novel therapeutic approaches to enhance anti-tumor immune responses. Here, we describe a novel cytotoxicity co-culture assay that circumvents the problem of highly variable allogeneic respons...

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Detalles Bibliográficos
Autores principales:	Nelson, Nadine, Lopez-Pelaez, Marta, Palazon, Asis, Poon, Edmund, De La Roche, Maike, Barry, Simon, Valge-Archer, Viia, Wilkinson, Robert W., Dovedi, Simon J., Smith, Paul D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682348/ https://www.ncbi.nlm.nih.gov/pubmed/31413906 http://dx.doi.org/10.1080/2162402X.2019.1599635

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