Cargando…
GCN-5/PGC-1α signaling is activated and associated with metabolism in cyclin E1-driven ovarian cancer
Aim: We previously found Cyclin E1-driven high grade serous ovarian cancer (HGSOC) showed metabolic shift. In this study, we aimed to elucidate signaling pathway therein. Methods: In silico reproduction of TCGA ovarian cancer dataset and pathway analysis were performed. Candidate metabolic pathway w...
Autores principales: | Guo, Ting, Li, Bin, Gu, Chao, Chen, Xiuying, Han, Mengxin, Liu, Xiaocheng, Xu, Congjian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682509/ https://www.ncbi.nlm.nih.gov/pubmed/31313989 http://dx.doi.org/10.18632/aging.102082 |
Ejemplares similares
-
PGC‐1α inhibits polyamine metabolism in Cyclin E1‐driven ovarian cancer
por: Guo, Ting, et al.
Publicado: (2019) -
COLGALT2 is overexpressed in ovarian cancer and interacts with PLOD3
por: Guo, Ting, et al.
Publicado: (2021) -
Cyclin D1 Represses Gluconeogenesis via Inhibition of the Transcriptional Coactivator PGC1α
por: Bhalla, Kavita, et al.
Publicado: (2014) -
TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance
por: Lynch, Matthew R., et al.
Publicado: (2019) -
TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance
por: Lynch, Matthew R., et al.
Publicado: (2020)