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Furin‐mediated protein processing in infectious diseases and cancer

Proteolytic cleavage regulates numerous processes in health and disease. One key player is the ubiquitously expressed serine protease furin, which cleaves a plethora of proteins at polybasic recognition motifs. Mammalian substrates of furin include cytokines, hormones, growth factors and receptors....

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Detalles Bibliográficos
Autores principales: Braun, Elisabeth, Sauter, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682551/
https://www.ncbi.nlm.nih.gov/pubmed/31406574
http://dx.doi.org/10.1002/cti2.1073