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Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APP(swe)/PS1(ΔE9) Transgenic Mice

Insulin-like growth factor-1 (IGF-1) is a pleiotropic molecule with neurotrophic and immunomodulatory functions. Knowing the capacity of chronically activated microglia to produce IGF-1 may therefore show essential to promote beneficial microglial functions in Alzheimer’s disease (AD). Here, we inve...

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Detalles Bibliográficos
Autores principales:	Myhre, Christa Løth, Thygesen, Camilla, Villadsen, Birgitte, Vollerup, Jeanette, Ilkjær, Laura, Krohn, Katrine Tækker, Grebing, Manuela, Zhao, Shuainan, Khan, Asif Manzoor, Dissing-Olesen, Lasse, Jensen, Morten Skovgaard, Babcock, Alicia A., Finsen, Bente
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682662/ https://www.ncbi.nlm.nih.gov/pubmed/31417357 http://dx.doi.org/10.3389/fncel.2019.00308

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