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Regulatory T Cells Promote Overexpression of Lgr5 on Gastric Cancer Cells via TGF-beta1 and Confer Poor Prognosis in Gastric Cancer

Background: The leucine-rich repeat containing G protein-coupled receptor 5 (Lgr5) is considered a cancer stem cell marker, and is often overexpressed in tumors. The interaction between Lgr5 and the immune-related tumor microenvironment is not completely understood. The aim of this study was to exam...

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Detalles Bibliográficos
Autores principales:	Liu, Xiao-Sun, Lin, Xian-Ke, Mei, Ying, Ahmad, Sabir, Yan, Chong-Xian, Jin, Hai-Long, Yu, Hang, Chen, Chao, Lin, Cai-Zhao, Yu, Ji-Ren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682668/ https://www.ncbi.nlm.nih.gov/pubmed/31417548 http://dx.doi.org/10.3389/fimmu.2019.01741

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