Cargando…

Therapeutic Modulation of the Complement Cascade in Stroke

Stroke is a leading cause of death and disability worldwide and an increasing number of ischemic stroke patients are undergoing pharmacological and mechanical reperfusion. Both human and experimental models of reperfused ischemic stroke have implicated the complement cascade in secondary tissue inju...

Descripción completa

Detalles Bibliográficos
Autores principales:	Clarke, Alison R., Christophe, Brandon R., Khahera, Anadjeet, Sim, Justin L., Connolly, E. Sander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682670/ https://www.ncbi.nlm.nih.gov/pubmed/31417544 http://dx.doi.org/10.3389/fimmu.2019.01723

Ejemplares similares

The Complement Cascade as a Mediator of Human Malignant Hematopoietic Cell Trafficking
por: Lenkiewicz, Anna, et al.
Publicado: (2019)

The Emerging Link Between the Complement Cascade and Purinergic Signaling in Stress Hematopoiesis
por: Ratajczak, Mariusz Z., et al.
Publicado: (2018)

Combining SPR with atomic-force microscopy enables single-molecule insights into activation and suppression of the complement cascade
por: Makou, Elisavet, et al.
Publicado: (2019)

Editorial: Therapeutic Modulation of the Complement System: Clinical Indications and Emerging Drug Leads
por: Mastellos, Dimitrios C., et al.
Publicado: (2020)

Complement Therapeutics in Autoimmune Disease
por: Thurman, Joshua M., et al.
Publicado: (2019)

Complement Therapeutics in the Multi-Organ Donor: Do or Don't?
por: van Zanden, Judith E., et al.
Publicado: (2019)

Complement in Thrombotic Microangiopathies: Unraveling Ariadne's Thread Into the Labyrinth of Complement Therapeutics
por: Gavriilaki, Eleni, et al.
Publicado: (2019)

Therapeutic Modulation of the Complement System in Kidney Transplantation: Clinical Indications and Emerging Drug Leads
por: Tatapudi, Vasishta S., et al.
Publicado: (2019)

Complement-Independent Modulation of Influenza A Virus Infection by Factor H
por: Murugaiah, Valarmathy, et al.
Publicado: (2020)

C1 Complex: An Adaptable Proteolytic Module for Complement and Non-Complement Functions
por: Lu, Jinhua, et al.
Publicado: (2017)

The Challenges and Promise of Complement Therapeutics for Ocular Diseases
por: Park, Dong Ho, et al.
Publicado: (2019)

Complement receptor is an inhibitor of the complement cascade
Publicado: (1981)

Targeting the Complement Pathway as a Therapeutic Strategy in Lung Cancer
por: Kleczko, Emily K., et al.
Publicado: (2019)

Complement and coagulation cascades in trauma
por: Satyam, Abhigyan, et al.
Publicado: (2019)

Osteoarthritis and the Complement Cascade
por: Silawal, Sandeep, et al.
Publicado: (2018)

Pathogenic Role of Complement in Antiphospholipid Syndrome and Therapeutic Implications
por: Tedesco, Francesco, et al.
Publicado: (2018)

Complement Inhibition in Coronavirus Disease (COVID)-19: A Neglected Therapeutic Option
por: Stahel, Philip F., et al.
Publicado: (2020)

Tissue plasminogen activator mediates deleterious complement cascade activation in stroke
por: Zhao, Xue-Jun, et al.
Publicado: (2017)

Complement Component 3 Negatively Regulates Antibody Response by Modulation of Red Blood Cell Antigen
por: Mener, Amanda, et al.
Publicado: (2018)

Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System
por: Carpanini, Sarah M., et al.
Publicado: (2019)

Current and Future Approaches for Monitoring Responses to Anti-complement Therapeutics
por: Mohebnasab, Maedeh, et al.
Publicado: (2019)

Viral Evasion of the Complement System and Its Importance for Vaccines and Therapeutics
por: Mellors, Jack, et al.
Publicado: (2020)

The Importance of Catheter Angiography in Computed Tomography Angiography-Negative Subarachnoid Hemorrhage
por: Haider, Ali S, et al.
Publicado: (2017)

Modulation of the Complement System by Neoplastic Disease of the Central Nervous System
por: Yarmoska, Steven K., et al.
Publicado: (2021)

Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue
por: Fahnoe, Kelly C., et al.
Publicado: (2022)

The Complement Cascade and Renal Disease
por: Kościelska-Kasprzak, Katarzyna, et al.
Publicado: (2013)

Platelets and the complement cascade in atherosclerosis
por: Patzelt, Johannes, et al.
Publicado: (2015)

Immunological Basis of the Endometriosis: The Complement System as a Potential Therapeutic Target
por: Agostinis, Chiara, et al.
Publicado: (2021)

Complement Factor H Family Proteins Modulate Monocyte and Neutrophil Granulocyte Functions
por: Kárpáti, Éva, et al.
Publicado: (2021)

Pathophysiological Mechanisms Underlying Idiopathic Normal Pressure Hydrocephalus: A Review of Recent Insights
por: Bonney, Phillip A., et al.
Publicado: (2022)

Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies
por: Zarantonello, Alessandra, et al.
Publicado: (2021)

Complement Factor I Variants in Complement-Mediated Renal Diseases
por: Zhang, Yuzhou, et al.
Publicado: (2022)

Complement C1s as a diagnostic marker and therapeutic target: Progress and propective
por: Ye, Jun, et al.
Publicado: (2022)

IMMU-09. MODULATING THE MYELOID POPULATION IN DIPG MODELS WITH ONCOLYTIC VIRUS AND COMPLEMENT INHIBITORS SHOWS THERAPEUTIC EFFICACY
por: Puigdelloses, Montserrat, et al.
Publicado: (2021)

The Promiscuous Profile of Complement Receptor 3 in Ligand Binding, Immune Modulation, and Pathophysiology
por: Lamers, Christina, et al.
Publicado: (2021)

Evaluating the comorbidities of age and cigarette smoking on stroke outcomes in the context of anti-complement mitigation strategies
por: Couch, Christine, et al.
Publicado: (2023)

Complement in the Pathophysiology of the Antiphospholipid Syndrome
por: Chaturvedi, Shruti, et al.
Publicado: (2019)

Understanding the Connection Between Common Stroke Comorbidities, Their Associated Inflammation, and the Course of the Cerebral Ischemia/Reperfusion Cascade
por: Przykaza, Łukasz
Publicado: (2021)

Exosomes Derived From Heat Stroke Cases Carry miRNAs Associated With Inflammation and Coagulation Cascade
por: Li, Yue, et al.
Publicado: (2021)

Complement Inhibition Promotes Endogenous Neurogenesis and Sustained Anti-Inflammatory Neuroprotection following Reperfused Stroke
por: Ducruet, Andrew F., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_mm67do62llubv4dafcanp6u0aa