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Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort

In low- and middle-income countries, the protective effect of breastfeeding against infections is well established, but in high-income countries, the effect could be weakened by higher hygienic conditions. We aimed to examine the association between breastfeeding and infections in the first 2 years...

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Autores principales: Davisse-Paturet, Camille, Adel-Patient, Karine, Divaret-Chauveau, Amandine, Pierson, Juliette, Lioret, Sandrine, Cheminat, Marie, Dufourg, Marie-Noëlle, Charles, Marie-Aline, de Lauzon-Guillain, Blandine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682893/
https://www.ncbi.nlm.nih.gov/pubmed/31311192
http://dx.doi.org/10.3390/nu11071607
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author Davisse-Paturet, Camille
Adel-Patient, Karine
Divaret-Chauveau, Amandine
Pierson, Juliette
Lioret, Sandrine
Cheminat, Marie
Dufourg, Marie-Noëlle
Charles, Marie-Aline
de Lauzon-Guillain, Blandine
author_facet Davisse-Paturet, Camille
Adel-Patient, Karine
Divaret-Chauveau, Amandine
Pierson, Juliette
Lioret, Sandrine
Cheminat, Marie
Dufourg, Marie-Noëlle
Charles, Marie-Aline
de Lauzon-Guillain, Blandine
author_sort Davisse-Paturet, Camille
collection PubMed
description In low- and middle-income countries, the protective effect of breastfeeding against infections is well established, but in high-income countries, the effect could be weakened by higher hygienic conditions. We aimed to examine the association between breastfeeding and infections in the first 2 years of life, in a high-income country with relatively short breastfeeding duration. Among 10,349 young children from the nationwide Etude Longitudinale Française depuis l’Enfance (ELFE) birth cohort, breastfeeding and parent-reported hospitalizations, bronchiolitis and otitis events, and antibiotic use were prospectively collected up to 2 years. Never-breastfed infants were used as reference group. Any breastfeeding for <3 months was associated with higher risks of hospitalizations from gastrointestinal infections or fever. Predominant breastfeeding for <1 month was associated with higher risk of a single hospital admission while predominant breastfeeding for ≥3 months was associated with a lower risk of long duration (≥4 nights) of hospitalization. Ever breastfeeding was associated with lower risk of antibiotic use. This study confirmed the well-known associations between breastfeeding and hospitalizations but also highlighted a strong inverse association between breastfeeding and antibiotic use. Although we cannot infer causality from this observational study, this finding is worth highlighting in a context of rising concern regarding antibiotic resistance.
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spelling pubmed-66828932019-08-09 Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort Davisse-Paturet, Camille Adel-Patient, Karine Divaret-Chauveau, Amandine Pierson, Juliette Lioret, Sandrine Cheminat, Marie Dufourg, Marie-Noëlle Charles, Marie-Aline de Lauzon-Guillain, Blandine Nutrients Article In low- and middle-income countries, the protective effect of breastfeeding against infections is well established, but in high-income countries, the effect could be weakened by higher hygienic conditions. We aimed to examine the association between breastfeeding and infections in the first 2 years of life, in a high-income country with relatively short breastfeeding duration. Among 10,349 young children from the nationwide Etude Longitudinale Française depuis l’Enfance (ELFE) birth cohort, breastfeeding and parent-reported hospitalizations, bronchiolitis and otitis events, and antibiotic use were prospectively collected up to 2 years. Never-breastfed infants were used as reference group. Any breastfeeding for <3 months was associated with higher risks of hospitalizations from gastrointestinal infections or fever. Predominant breastfeeding for <1 month was associated with higher risk of a single hospital admission while predominant breastfeeding for ≥3 months was associated with a lower risk of long duration (≥4 nights) of hospitalization. Ever breastfeeding was associated with lower risk of antibiotic use. This study confirmed the well-known associations between breastfeeding and hospitalizations but also highlighted a strong inverse association between breastfeeding and antibiotic use. Although we cannot infer causality from this observational study, this finding is worth highlighting in a context of rising concern regarding antibiotic resistance. MDPI 2019-07-15 /pmc/articles/PMC6682893/ /pubmed/31311192 http://dx.doi.org/10.3390/nu11071607 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Davisse-Paturet, Camille
Adel-Patient, Karine
Divaret-Chauveau, Amandine
Pierson, Juliette
Lioret, Sandrine
Cheminat, Marie
Dufourg, Marie-Noëlle
Charles, Marie-Aline
de Lauzon-Guillain, Blandine
Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort
title Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort
title_full Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort
title_fullStr Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort
title_full_unstemmed Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort
title_short Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort
title_sort breastfeeding status and duration and infections, hospitalizations for infections, and antibiotic use in the first two years of life in the elfe cohort
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682893/
https://www.ncbi.nlm.nih.gov/pubmed/31311192
http://dx.doi.org/10.3390/nu11071607
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