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Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort
In low- and middle-income countries, the protective effect of breastfeeding against infections is well established, but in high-income countries, the effect could be weakened by higher hygienic conditions. We aimed to examine the association between breastfeeding and infections in the first 2 years...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682893/ https://www.ncbi.nlm.nih.gov/pubmed/31311192 http://dx.doi.org/10.3390/nu11071607 |
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author | Davisse-Paturet, Camille Adel-Patient, Karine Divaret-Chauveau, Amandine Pierson, Juliette Lioret, Sandrine Cheminat, Marie Dufourg, Marie-Noëlle Charles, Marie-Aline de Lauzon-Guillain, Blandine |
author_facet | Davisse-Paturet, Camille Adel-Patient, Karine Divaret-Chauveau, Amandine Pierson, Juliette Lioret, Sandrine Cheminat, Marie Dufourg, Marie-Noëlle Charles, Marie-Aline de Lauzon-Guillain, Blandine |
author_sort | Davisse-Paturet, Camille |
collection | PubMed |
description | In low- and middle-income countries, the protective effect of breastfeeding against infections is well established, but in high-income countries, the effect could be weakened by higher hygienic conditions. We aimed to examine the association between breastfeeding and infections in the first 2 years of life, in a high-income country with relatively short breastfeeding duration. Among 10,349 young children from the nationwide Etude Longitudinale Française depuis l’Enfance (ELFE) birth cohort, breastfeeding and parent-reported hospitalizations, bronchiolitis and otitis events, and antibiotic use were prospectively collected up to 2 years. Never-breastfed infants were used as reference group. Any breastfeeding for <3 months was associated with higher risks of hospitalizations from gastrointestinal infections or fever. Predominant breastfeeding for <1 month was associated with higher risk of a single hospital admission while predominant breastfeeding for ≥3 months was associated with a lower risk of long duration (≥4 nights) of hospitalization. Ever breastfeeding was associated with lower risk of antibiotic use. This study confirmed the well-known associations between breastfeeding and hospitalizations but also highlighted a strong inverse association between breastfeeding and antibiotic use. Although we cannot infer causality from this observational study, this finding is worth highlighting in a context of rising concern regarding antibiotic resistance. |
format | Online Article Text |
id | pubmed-6682893 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66828932019-08-09 Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort Davisse-Paturet, Camille Adel-Patient, Karine Divaret-Chauveau, Amandine Pierson, Juliette Lioret, Sandrine Cheminat, Marie Dufourg, Marie-Noëlle Charles, Marie-Aline de Lauzon-Guillain, Blandine Nutrients Article In low- and middle-income countries, the protective effect of breastfeeding against infections is well established, but in high-income countries, the effect could be weakened by higher hygienic conditions. We aimed to examine the association between breastfeeding and infections in the first 2 years of life, in a high-income country with relatively short breastfeeding duration. Among 10,349 young children from the nationwide Etude Longitudinale Française depuis l’Enfance (ELFE) birth cohort, breastfeeding and parent-reported hospitalizations, bronchiolitis and otitis events, and antibiotic use were prospectively collected up to 2 years. Never-breastfed infants were used as reference group. Any breastfeeding for <3 months was associated with higher risks of hospitalizations from gastrointestinal infections or fever. Predominant breastfeeding for <1 month was associated with higher risk of a single hospital admission while predominant breastfeeding for ≥3 months was associated with a lower risk of long duration (≥4 nights) of hospitalization. Ever breastfeeding was associated with lower risk of antibiotic use. This study confirmed the well-known associations between breastfeeding and hospitalizations but also highlighted a strong inverse association between breastfeeding and antibiotic use. Although we cannot infer causality from this observational study, this finding is worth highlighting in a context of rising concern regarding antibiotic resistance. MDPI 2019-07-15 /pmc/articles/PMC6682893/ /pubmed/31311192 http://dx.doi.org/10.3390/nu11071607 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Davisse-Paturet, Camille Adel-Patient, Karine Divaret-Chauveau, Amandine Pierson, Juliette Lioret, Sandrine Cheminat, Marie Dufourg, Marie-Noëlle Charles, Marie-Aline de Lauzon-Guillain, Blandine Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort |
title | Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort |
title_full | Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort |
title_fullStr | Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort |
title_full_unstemmed | Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort |
title_short | Breastfeeding Status and Duration and Infections, Hospitalizations for Infections, and Antibiotic Use in the First Two Years of Life in the ELFE Cohort |
title_sort | breastfeeding status and duration and infections, hospitalizations for infections, and antibiotic use in the first two years of life in the elfe cohort |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682893/ https://www.ncbi.nlm.nih.gov/pubmed/31311192 http://dx.doi.org/10.3390/nu11071607 |
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