Cargando…
Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A
The lysine-specific histone demethylase 1A (LSD1) also known as lysine (K)-specific demethylase 1A (KDM1A) is a central epigenetic regulator of metabolic reprogramming in obesity-associated diseases, neurological disorders, and cancer. Here, we evaluated the ability of oleacein, a biophenol secoirid...
Autores principales: | Cuyàs, Elisabet, Gumuzio, Juan, Lozano-Sánchez, Jesús, Carreras, David, Verdura, Sara, Llorach-Parés, Laura, Sanchez-Martinez, Melchor, Selga, Elisabet, Pérez, Guillermo J., Scornik, Fabiana S., Brugada, Ramon, Bosch-Barrera, Joaquim, Segura-Carretero, Antonio, Martin, Ángel G., Encinar, José Antonio, Menendez, Javier A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683035/ https://www.ncbi.nlm.nih.gov/pubmed/31331073 http://dx.doi.org/10.3390/nu11071656 |
Ejemplares similares
-
Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity
por: Cuyàs, Elisabet, et al.
Publicado: (2020) -
Metformin directly targets the H3K27me3 demethylase KDM6A/UTX
por: Cuyàs, Elisabet, et al.
Publicado: (2018) -
The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes
por: Cuyàs, Elisabet, et al.
Publicado: (2020) -
Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells
por: Corominas-Faja, Bruna, et al.
Publicado: (2018) -
Targeting Histone Demethylase LSD1/KDM1a in Neurodegenerative Diseases
por: Ambrosio, Susanna, et al.
Publicado: (2018)