Cargando…

Phytochemicals in Prostate Cancer: From Bioactive Molecules to Upcoming Therapeutic Agents

Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and the most commonly diagnosed cancer among men. Traditional plants have been applied to handle various diseases and to develop new drugs. Medicinal plants are potential sources of natural bioactive compounds that in...

Descripción completa

Detalles Bibliográficos
Autores principales: Salehi, Bahare, Fokou, Patrick Valere Tsouh, Yamthe, Lauve Rachel Tchokouaha, Tali, Brice Tchatat, Adetunji, Charles Oluwaseun, Rahavian, Amirhossein, Mudau, Fhatuwani Nixwell, Martorell, Miquel, Setzer, William N., Rodrigues, Célia F., Martins, Natália, Cho, William C., Sharifi-Rad, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683070/
https://www.ncbi.nlm.nih.gov/pubmed/31261861
http://dx.doi.org/10.3390/nu11071483
Descripción
Sumario:Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and the most commonly diagnosed cancer among men. Traditional plants have been applied to handle various diseases and to develop new drugs. Medicinal plants are potential sources of natural bioactive compounds that include alkaloids, phenolic compounds, terpenes, and steroids. Many of these naturally-occurring bioactive constituents possess promising chemopreventive properties. In this sense, the aim of the present review is to provide a detailed overview of the role of plant-derived phytochemicals in prostate cancers, including the contribution of plant extracts and its corresponding isolated compounds.