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The lipid-dependent structure and function of LacY can be recapitulated and analyzed in phospholipid-containing detergent micelles

Membrane proteins play key roles in cellular functions, their activity mainly depending on their topological arrangement in membranes. Structural studies of membrane proteins have long adopted a protein-centric view regarding the determinants of membrane protein topology and function. Several studie...

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Detalles Bibliográficos
Autores principales: Vitrac, Heidi, Mallampalli, Venkata K P S, Bogdanov, Mikhail, Dowhan, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683142/
https://www.ncbi.nlm.nih.gov/pubmed/31383935
http://dx.doi.org/10.1038/s41598-019-47824-y

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