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Cyclooxygenase inhibitors impair CD4 T cell immunity and exacerbate Mycobacterium tuberculosis infection in aerosol-challenged mice
Tuberculosis, caused by infection with Mycobacterium tuberculosis (Mtb), kills over 1.6 million people each year despite availability of antibiotics. The increase in drug resistant Mtb strains is a major public health emergency and host-directed therapy as adjunct to antibiotic treatment has gained...
Autores principales: | Mortensen, Rasmus, Clemmensen, Helena Strand, Woodworth, Joshua S., Therkelsen, Marie Louise, Mustafa, Tehmina, Tonby, Kristian, Jenum, Synne, Agger, Else Marie, Dyrhol-Riise, Anne Ma, Andersen, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683187/ https://www.ncbi.nlm.nih.gov/pubmed/31396568 http://dx.doi.org/10.1038/s42003-019-0530-3 |
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