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Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner
To support frequency-coded information transfer, mammalian synapses tightly synchronize neurotransmitter release to action potentials (APs). However, release desynchronizes during AP trains, especially at room temperature. Here we show that suppression of asynchronous release by Synaptotagmin-1 (Syt...
Autores principales: | Huson, Vincent, van Boven, Maaike A., Stuefer, Alexia, Verhage, Matthijs, Cornelisse, L. Niels |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683208/ https://www.ncbi.nlm.nih.gov/pubmed/31383906 http://dx.doi.org/10.1038/s41598-019-47487-9 |
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