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Accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction
OBJECTIVE: Left ventricle (LV) geometry and dyssynchrony are associated with LV remodeling after acute myocardial infarction (AMI). The aim of this prospective study was to assess the diagnostic value of new three-dimensional echocardiography (3DE) parameters [sphericity (SI) and systolic dyssynchro...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kare Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683215/ https://www.ncbi.nlm.nih.gov/pubmed/31264652 http://dx.doi.org/10.14744/AnatolJCardiol.2019.02844 |
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author | Karuzas, Arnas Rumbinaite, Egle Verikas, Dovydas Ptasinskas, Tomas Muckiene, Gintare Kazakauskaite, Egle Zabiela, Vytautas Jurkevicius, Renaldas Vaskelyte, Jolanta Justina Zaliunas, Remigijus Zaliaduonyte-Peksiene, Diana |
author_facet | Karuzas, Arnas Rumbinaite, Egle Verikas, Dovydas Ptasinskas, Tomas Muckiene, Gintare Kazakauskaite, Egle Zabiela, Vytautas Jurkevicius, Renaldas Vaskelyte, Jolanta Justina Zaliunas, Remigijus Zaliaduonyte-Peksiene, Diana |
author_sort | Karuzas, Arnas |
collection | PubMed |
description | OBJECTIVE: Left ventricle (LV) geometry and dyssynchrony are associated with LV remodeling after acute myocardial infarction (AMI). The aim of this prospective study was to assess the diagnostic value of new three-dimensional echocardiography (3DE) parameters [sphericity (SI) and systolic dyssynchrony indexes (SDI)] for the prediction of LV remodeling after AMI and to compare them with two-dimensional echocardiography (2DE) parameters. METHODS: 2DE and 3DE were performed in 75 patients with AMI within 3 days from the onset of MI and 6 months later. LV remodeling was defined as a ≥15% increase in the LV end-diastolic volume (EDV) at follow-up. 3D SI was calculated by dividing EDV by the volume of a sphere whose diameter was derived from the major end-diastolic LV long axis. SDI was considered as a standard deviation of the time from cardiac cycle onset to minimum systolic volume in 16 LV segments. RESULTS: LV remodeling was identified in 34 (45%) patients using the 2DE method and in 22 (29%) patients using the 3DE method. Evaluated 3DE parameters, such as EDV [area under the receiver operating characteristic (ROC) curve (AUC) 0.742, sensitivity 71%, specificity 79%], end-systolic volume (AUC 0.729, sensitivity 69%, specificity 78%), SDI (AUC 0.777, sensitivity 73%, specificity 77%), and SI, had significant prognostic value for LV remodeling. According to the AUC, the highest predictive value had 3D SI (AUC 0.957, sensitivity 90%, specificity 91%). CONCLUSION: 3DE parameters, especially 3D SI and SDI, play important roles in the prediction of LV remodeling after AMI and can be used in clinical practice. |
format | Online Article Text |
id | pubmed-6683215 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Kare Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-66832152019-08-19 Accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction Karuzas, Arnas Rumbinaite, Egle Verikas, Dovydas Ptasinskas, Tomas Muckiene, Gintare Kazakauskaite, Egle Zabiela, Vytautas Jurkevicius, Renaldas Vaskelyte, Jolanta Justina Zaliunas, Remigijus Zaliaduonyte-Peksiene, Diana Anatol J Cardiol Original Investigation OBJECTIVE: Left ventricle (LV) geometry and dyssynchrony are associated with LV remodeling after acute myocardial infarction (AMI). The aim of this prospective study was to assess the diagnostic value of new three-dimensional echocardiography (3DE) parameters [sphericity (SI) and systolic dyssynchrony indexes (SDI)] for the prediction of LV remodeling after AMI and to compare them with two-dimensional echocardiography (2DE) parameters. METHODS: 2DE and 3DE were performed in 75 patients with AMI within 3 days from the onset of MI and 6 months later. LV remodeling was defined as a ≥15% increase in the LV end-diastolic volume (EDV) at follow-up. 3D SI was calculated by dividing EDV by the volume of a sphere whose diameter was derived from the major end-diastolic LV long axis. SDI was considered as a standard deviation of the time from cardiac cycle onset to minimum systolic volume in 16 LV segments. RESULTS: LV remodeling was identified in 34 (45%) patients using the 2DE method and in 22 (29%) patients using the 3DE method. Evaluated 3DE parameters, such as EDV [area under the receiver operating characteristic (ROC) curve (AUC) 0.742, sensitivity 71%, specificity 79%], end-systolic volume (AUC 0.729, sensitivity 69%, specificity 78%), SDI (AUC 0.777, sensitivity 73%, specificity 77%), and SI, had significant prognostic value for LV remodeling. According to the AUC, the highest predictive value had 3D SI (AUC 0.957, sensitivity 90%, specificity 91%). CONCLUSION: 3DE parameters, especially 3D SI and SDI, play important roles in the prediction of LV remodeling after AMI and can be used in clinical practice. Kare Publishing 2019 2019-05-08 /pmc/articles/PMC6683215/ /pubmed/31264652 http://dx.doi.org/10.14744/AnatolJCardiol.2019.02844 Text en Copyright: © 2019 Turkish Society of Cardiology http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License |
spellingShingle | Original Investigation Karuzas, Arnas Rumbinaite, Egle Verikas, Dovydas Ptasinskas, Tomas Muckiene, Gintare Kazakauskaite, Egle Zabiela, Vytautas Jurkevicius, Renaldas Vaskelyte, Jolanta Justina Zaliunas, Remigijus Zaliaduonyte-Peksiene, Diana Accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction |
title | Accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction |
title_full | Accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction |
title_fullStr | Accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction |
title_full_unstemmed | Accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction |
title_short | Accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction |
title_sort | accuracy of three-dimensional systolic dyssynchrony and sphericity indexes for identifying early left ventricular remodeling after acute myocardial infarction |
topic | Original Investigation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683215/ https://www.ncbi.nlm.nih.gov/pubmed/31264652 http://dx.doi.org/10.14744/AnatolJCardiol.2019.02844 |
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