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Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults
Emerging research indicates that nuts are a source of health-promoting compounds demonstrating cardioprotective benefits. However, most studies have assessed the effect of single nuts rather than a nut mixture. The objective of this study was, therefore, to examine the effect of mixed-nut consumptio...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683273/ https://www.ncbi.nlm.nih.gov/pubmed/31261928 http://dx.doi.org/10.3390/nu11071488 |
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author | Abbaspour, Nazanin Roberts, Traci Hooshmand, Shirin Kern, Mark Hong, Mee Young |
author_facet | Abbaspour, Nazanin Roberts, Traci Hooshmand, Shirin Kern, Mark Hong, Mee Young |
author_sort | Abbaspour, Nazanin |
collection | PubMed |
description | Emerging research indicates that nuts are a source of health-promoting compounds demonstrating cardioprotective benefits. However, most studies have assessed the effect of single nuts rather than a nut mixture. The objective of this study was, therefore, to examine the effect of mixed-nut consumption on cardiovascular disease (CVD) risk factors in overweight and obese adults. In a randomized, parallel-arm, controlled trial, 48 participants consumed isocaloric (250 kcal) amounts of pretzels or mixed-nuts. Body weight (BW) (p = 0.024), BMI (p = 0.043), and insulin levels (p = 0.032) were significantly lower in the nut group compared to the pretzel group. Mixed-nut consumption also significantly reduced glucose (p = 0.04) and insulin (p = 0.032) levels after 4 and 8 weeks compared to baseline, respectively. Lactate dehydrogenase of the nut group was significantly lower than the pretzel group (p = 0.002). No significant differences were detected between groups for triglycerides, LDL-C, and HDL-C. However, pretzel consumption increased triglycerides (p = 0.048) from 4 weeks to 8 weeks. Moreover, LDL-C increased (p = 0.038) while HDL-C transiently decreased (p = 0.044) from baseline to 4 weeks. No significant lipid changes were detected within the nut group. Our results suggest that supplementing the diet with mixed-nuts could improve CVD risk factors by improving BW and glucose regulation in comparison to a common carbohydrate-rich snack without promoting the negative effects on lipids detected with pretzels. |
format | Online Article Text |
id | pubmed-6683273 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66832732019-08-09 Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults Abbaspour, Nazanin Roberts, Traci Hooshmand, Shirin Kern, Mark Hong, Mee Young Nutrients Article Emerging research indicates that nuts are a source of health-promoting compounds demonstrating cardioprotective benefits. However, most studies have assessed the effect of single nuts rather than a nut mixture. The objective of this study was, therefore, to examine the effect of mixed-nut consumption on cardiovascular disease (CVD) risk factors in overweight and obese adults. In a randomized, parallel-arm, controlled trial, 48 participants consumed isocaloric (250 kcal) amounts of pretzels or mixed-nuts. Body weight (BW) (p = 0.024), BMI (p = 0.043), and insulin levels (p = 0.032) were significantly lower in the nut group compared to the pretzel group. Mixed-nut consumption also significantly reduced glucose (p = 0.04) and insulin (p = 0.032) levels after 4 and 8 weeks compared to baseline, respectively. Lactate dehydrogenase of the nut group was significantly lower than the pretzel group (p = 0.002). No significant differences were detected between groups for triglycerides, LDL-C, and HDL-C. However, pretzel consumption increased triglycerides (p = 0.048) from 4 weeks to 8 weeks. Moreover, LDL-C increased (p = 0.038) while HDL-C transiently decreased (p = 0.044) from baseline to 4 weeks. No significant lipid changes were detected within the nut group. Our results suggest that supplementing the diet with mixed-nuts could improve CVD risk factors by improving BW and glucose regulation in comparison to a common carbohydrate-rich snack without promoting the negative effects on lipids detected with pretzels. MDPI 2019-06-29 /pmc/articles/PMC6683273/ /pubmed/31261928 http://dx.doi.org/10.3390/nu11071488 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Abbaspour, Nazanin Roberts, Traci Hooshmand, Shirin Kern, Mark Hong, Mee Young Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults |
title | Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults |
title_full | Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults |
title_fullStr | Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults |
title_full_unstemmed | Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults |
title_short | Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults |
title_sort | mixed nut consumption may improve cardiovascular disease risk factors in overweight and obese adults |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683273/ https://www.ncbi.nlm.nih.gov/pubmed/31261928 http://dx.doi.org/10.3390/nu11071488 |
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