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Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults

Emerging research indicates that nuts are a source of health-promoting compounds demonstrating cardioprotective benefits. However, most studies have assessed the effect of single nuts rather than a nut mixture. The objective of this study was, therefore, to examine the effect of mixed-nut consumptio...

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Autores principales: Abbaspour, Nazanin, Roberts, Traci, Hooshmand, Shirin, Kern, Mark, Hong, Mee Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683273/
https://www.ncbi.nlm.nih.gov/pubmed/31261928
http://dx.doi.org/10.3390/nu11071488
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author Abbaspour, Nazanin
Roberts, Traci
Hooshmand, Shirin
Kern, Mark
Hong, Mee Young
author_facet Abbaspour, Nazanin
Roberts, Traci
Hooshmand, Shirin
Kern, Mark
Hong, Mee Young
author_sort Abbaspour, Nazanin
collection PubMed
description Emerging research indicates that nuts are a source of health-promoting compounds demonstrating cardioprotective benefits. However, most studies have assessed the effect of single nuts rather than a nut mixture. The objective of this study was, therefore, to examine the effect of mixed-nut consumption on cardiovascular disease (CVD) risk factors in overweight and obese adults. In a randomized, parallel-arm, controlled trial, 48 participants consumed isocaloric (250 kcal) amounts of pretzels or mixed-nuts. Body weight (BW) (p = 0.024), BMI (p = 0.043), and insulin levels (p = 0.032) were significantly lower in the nut group compared to the pretzel group. Mixed-nut consumption also significantly reduced glucose (p = 0.04) and insulin (p = 0.032) levels after 4 and 8 weeks compared to baseline, respectively. Lactate dehydrogenase of the nut group was significantly lower than the pretzel group (p = 0.002). No significant differences were detected between groups for triglycerides, LDL-C, and HDL-C. However, pretzel consumption increased triglycerides (p = 0.048) from 4 weeks to 8 weeks. Moreover, LDL-C increased (p = 0.038) while HDL-C transiently decreased (p = 0.044) from baseline to 4 weeks. No significant lipid changes were detected within the nut group. Our results suggest that supplementing the diet with mixed-nuts could improve CVD risk factors by improving BW and glucose regulation in comparison to a common carbohydrate-rich snack without promoting the negative effects on lipids detected with pretzels.
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spelling pubmed-66832732019-08-09 Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults Abbaspour, Nazanin Roberts, Traci Hooshmand, Shirin Kern, Mark Hong, Mee Young Nutrients Article Emerging research indicates that nuts are a source of health-promoting compounds demonstrating cardioprotective benefits. However, most studies have assessed the effect of single nuts rather than a nut mixture. The objective of this study was, therefore, to examine the effect of mixed-nut consumption on cardiovascular disease (CVD) risk factors in overweight and obese adults. In a randomized, parallel-arm, controlled trial, 48 participants consumed isocaloric (250 kcal) amounts of pretzels or mixed-nuts. Body weight (BW) (p = 0.024), BMI (p = 0.043), and insulin levels (p = 0.032) were significantly lower in the nut group compared to the pretzel group. Mixed-nut consumption also significantly reduced glucose (p = 0.04) and insulin (p = 0.032) levels after 4 and 8 weeks compared to baseline, respectively. Lactate dehydrogenase of the nut group was significantly lower than the pretzel group (p = 0.002). No significant differences were detected between groups for triglycerides, LDL-C, and HDL-C. However, pretzel consumption increased triglycerides (p = 0.048) from 4 weeks to 8 weeks. Moreover, LDL-C increased (p = 0.038) while HDL-C transiently decreased (p = 0.044) from baseline to 4 weeks. No significant lipid changes were detected within the nut group. Our results suggest that supplementing the diet with mixed-nuts could improve CVD risk factors by improving BW and glucose regulation in comparison to a common carbohydrate-rich snack without promoting the negative effects on lipids detected with pretzels. MDPI 2019-06-29 /pmc/articles/PMC6683273/ /pubmed/31261928 http://dx.doi.org/10.3390/nu11071488 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Abbaspour, Nazanin
Roberts, Traci
Hooshmand, Shirin
Kern, Mark
Hong, Mee Young
Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults
title Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults
title_full Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults
title_fullStr Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults
title_full_unstemmed Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults
title_short Mixed Nut Consumption May Improve Cardiovascular Disease Risk Factors in Overweight and Obese Adults
title_sort mixed nut consumption may improve cardiovascular disease risk factors in overweight and obese adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683273/
https://www.ncbi.nlm.nih.gov/pubmed/31261928
http://dx.doi.org/10.3390/nu11071488
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