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Vitamin D and Obesity: Two Interacting Players in the Field of Infertility
Obesity plays an important role in human fertility in both genders. The same is true for vitamin D, for which accumulating evidence from observational human studies suggests a key role for both male and female fertility. In the latter case, however, robust data from relevant interventional studies a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683323/ https://www.ncbi.nlm.nih.gov/pubmed/31252555 http://dx.doi.org/10.3390/nu11071455 |
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author | Bosdou, Julia K. Konstantinidou, Eirini Anagnostis, Panagiotis Kolibianakis, Efstratios M. Goulis, Dimitrios G. |
author_facet | Bosdou, Julia K. Konstantinidou, Eirini Anagnostis, Panagiotis Kolibianakis, Efstratios M. Goulis, Dimitrios G. |
author_sort | Bosdou, Julia K. |
collection | PubMed |
description | Obesity plays an important role in human fertility in both genders. The same is true for vitamin D, for which accumulating evidence from observational human studies suggests a key role for both male and female fertility. In the latter case, however, robust data from relevant interventional studies are currently lacking. It is also not clear whether obesity and vitamin D deficiency, besides their independent effect on human infertility, act in synergy. Several pathogenetic mechanisms may be proposed as a linkage between vitamin D deficiency and obesity, with respect to infertility. In any case, the independent contribution of vitamin D deficiency in obese infertile states needs to be proven in interventional studies focusing on either vitamin D supplementation in obese or weight loss strategies in vitamin D-deficient infertile patients. |
format | Online Article Text |
id | pubmed-6683323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-66833232019-08-09 Vitamin D and Obesity: Two Interacting Players in the Field of Infertility Bosdou, Julia K. Konstantinidou, Eirini Anagnostis, Panagiotis Kolibianakis, Efstratios M. Goulis, Dimitrios G. Nutrients Review Obesity plays an important role in human fertility in both genders. The same is true for vitamin D, for which accumulating evidence from observational human studies suggests a key role for both male and female fertility. In the latter case, however, robust data from relevant interventional studies are currently lacking. It is also not clear whether obesity and vitamin D deficiency, besides their independent effect on human infertility, act in synergy. Several pathogenetic mechanisms may be proposed as a linkage between vitamin D deficiency and obesity, with respect to infertility. In any case, the independent contribution of vitamin D deficiency in obese infertile states needs to be proven in interventional studies focusing on either vitamin D supplementation in obese or weight loss strategies in vitamin D-deficient infertile patients. MDPI 2019-06-27 /pmc/articles/PMC6683323/ /pubmed/31252555 http://dx.doi.org/10.3390/nu11071455 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bosdou, Julia K. Konstantinidou, Eirini Anagnostis, Panagiotis Kolibianakis, Efstratios M. Goulis, Dimitrios G. Vitamin D and Obesity: Two Interacting Players in the Field of Infertility |
title | Vitamin D and Obesity: Two Interacting Players in the Field of Infertility |
title_full | Vitamin D and Obesity: Two Interacting Players in the Field of Infertility |
title_fullStr | Vitamin D and Obesity: Two Interacting Players in the Field of Infertility |
title_full_unstemmed | Vitamin D and Obesity: Two Interacting Players in the Field of Infertility |
title_short | Vitamin D and Obesity: Two Interacting Players in the Field of Infertility |
title_sort | vitamin d and obesity: two interacting players in the field of infertility |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683323/ https://www.ncbi.nlm.nih.gov/pubmed/31252555 http://dx.doi.org/10.3390/nu11071455 |
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