Palmitoylation is required for TNF-R1 signaling

BACKGROUND: Binding of tumor necrosis factor (TNF) to TNF-receptor 1 (TNF-R1) can induce either cell survival or cell death. The selection between these diametrically opposed effects depends on the subcellular location of TNF-R1: plasma membrane retention leads to survival, while endocytosis leads t...

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Detalles Bibliográficos
Autores principales: Zingler, Philipp, Särchen, Vinzenz, Glatter, Timo, Caning, Lotta, Saggau, Carina, Kathayat, Rahul S., Dickinson, Bryan C., Adam, Dieter, Schneider-Brachert, Wulf, Schütze, Stefan, Fritsch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683503/
https://www.ncbi.nlm.nih.gov/pubmed/31382980
http://dx.doi.org/10.1186/s12964-019-0405-8

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