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Update to the study protocol, including statistical analysis plan, for the multicentre, randomised controlled OuTSMART trial: a combined screening/treatment programme to prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies

BACKGROUND: Chronic rejection is the single biggest cause of premature kidney graft failure. HLA antibodies (Ab) are an established prognostic biomarker for premature graft failure so there is a need to test whether treatment decisions based on the presence of the biomarker can alter prognosis. The...

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Detalles Bibliográficos
Autores principales: Stringer, Dominic, Gardner, Leanne M., Peacock, Janet L., Rebollo-Mesa, Irene, Hilton, Rachel, Shaw, Olivia, Baker, Richard, Clark, Brendan, Thuraisingham, Raj C., Buckland, Matthew, Picton, Michael, Worthington, Judith, Borrows, Richard, Briggs, David, Shah, Sapna, Shiu, Kin Yee, McCullough, Keith, Phanish, Mysore, Hegarty, Janet, Stoves, John, Ahmed, Aimun, Ayub, Waqar, Horne, Robert, McCrone, Paul, Kelly, Joanna, Murphy, Caroline, Dorling, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683506/
https://www.ncbi.nlm.nih.gov/pubmed/31383029
http://dx.doi.org/10.1186/s13063-019-3602-2