EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

BACKGROUND: Atopic dermatitis (AD) is a common, complex, and highly heritable inflammatory skin disease. Genome-wide association studies offer opportunities to identify molecular targets for drug development. A risk locus on chromosome 11q13.5 lies between 2 candidate genes, EMSY and LRRC32 (leucine...

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Detalles Bibliográficos
Autores principales: Elias, Martina S., Wright, Sheila C., Remenyi, Judit, Abbott, James C., Bray, Susan E., Cole, Christian, Edwards, Sharon, Gierlinski, Marek, Glok, Mateusz, McGrath, John A., Nicholson, William V., Paternoster, Lavinia, Prescott, Alan R., Have, Sara Ten, Whitfield, Phillip D., Lamond, Angus I., Brown, Sara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683598/
https://www.ncbi.nlm.nih.gov/pubmed/31158401
http://dx.doi.org/10.1016/j.jaci.2019.05.024

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