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Myosin lever arm orientation in muscle determined with high angular resolution using bifunctional spin labels

Despite advances in x-ray crystallography, cryo-electron microscopy (cryo-EM), and fluorescence polarization, none of these techniques provide high-resolution structural information about the myosin light chain domain (LCD; lever arm) under ambient conditions in vertebrate muscle. Here, we measure t...

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Detalles Bibliográficos
Autores principales: Savich, Yahor, Binder, Benjamin P., Thompson, Andrew R., Thomas, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683674/
https://www.ncbi.nlm.nih.gov/pubmed/31227551
http://dx.doi.org/10.1085/jgp.201812210