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Myosin lever arm orientation in muscle determined with high angular resolution using bifunctional spin labels
Despite advances in x-ray crystallography, cryo-electron microscopy (cryo-EM), and fluorescence polarization, none of these techniques provide high-resolution structural information about the myosin light chain domain (LCD; lever arm) under ambient conditions in vertebrate muscle. Here, we measure t...
Autores principales: | Savich, Yahor, Binder, Benjamin P., Thompson, Andrew R., Thomas, David D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683674/ https://www.ncbi.nlm.nih.gov/pubmed/31227551 http://dx.doi.org/10.1085/jgp.201812210 |
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