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Spastin joins LDs and peroxisomes in the interorganelle contact ballet
Lipid droplets (LDs) store energy-rich fatty acids (FAs), but to harvest them, LDs donate FAs to peroxisomes for oxidation. In this issue, Chang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902061) identify M1 Spastin as an LD–peroxisome tether that interacts with ESCRT-III components...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683730/ https://www.ncbi.nlm.nih.gov/pubmed/31278079 http://dx.doi.org/10.1083/jcb.201906025 |
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author | Henne, W. Mike |
author_facet | Henne, W. Mike |
author_sort | Henne, W. Mike |
collection | PubMed |
description | Lipid droplets (LDs) store energy-rich fatty acids (FAs), but to harvest them, LDs donate FAs to peroxisomes for oxidation. In this issue, Chang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902061) identify M1 Spastin as an LD–peroxisome tether that interacts with ESCRT-III components to facilitate lipid exchange between these two organelles. |
format | Online Article Text |
id | pubmed-6683730 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-66837302020-02-05 Spastin joins LDs and peroxisomes in the interorganelle contact ballet Henne, W. Mike J Cell Biol Commentaries Lipid droplets (LDs) store energy-rich fatty acids (FAs), but to harvest them, LDs donate FAs to peroxisomes for oxidation. In this issue, Chang et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902061) identify M1 Spastin as an LD–peroxisome tether that interacts with ESCRT-III components to facilitate lipid exchange between these two organelles. Rockefeller University Press 2019-08-05 2019-07-05 /pmc/articles/PMC6683730/ /pubmed/31278079 http://dx.doi.org/10.1083/jcb.201906025 Text en © 2019 Henne http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Commentaries Henne, W. Mike Spastin joins LDs and peroxisomes in the interorganelle contact ballet |
title | Spastin joins LDs and peroxisomes in the interorganelle contact ballet |
title_full | Spastin joins LDs and peroxisomes in the interorganelle contact ballet |
title_fullStr | Spastin joins LDs and peroxisomes in the interorganelle contact ballet |
title_full_unstemmed | Spastin joins LDs and peroxisomes in the interorganelle contact ballet |
title_short | Spastin joins LDs and peroxisomes in the interorganelle contact ballet |
title_sort | spastin joins lds and peroxisomes in the interorganelle contact ballet |
topic | Commentaries |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683730/ https://www.ncbi.nlm.nih.gov/pubmed/31278079 http://dx.doi.org/10.1083/jcb.201906025 |
work_keys_str_mv | AT hennewmike spastinjoinsldsandperoxisomesintheinterorganellecontactballet |