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Developmentally regulated GTP-binding protein 1 modulates ciliogenesis via an interaction with Dishevelled

Cilia are critical for proper embryonic development and maintaining homeostasis. Although extensively studied, there are still significant gaps regarding the proteins involved in regulating ciliogenesis. Using the Xenopus laevis embryo, we show that Dishevelled (Dvl), a key Wnt signaling scaffold th...

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Detalles Bibliográficos
Autores principales: Lee, Moonsup, Hwang, Yoo-Seok, Yoon, Jaeho, Sun, Jian, Harned, Adam, Nagashima, Kunio, Daar, Ira O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683737/
https://www.ncbi.nlm.nih.gov/pubmed/31270137
http://dx.doi.org/10.1083/jcb.201811147