Neurexin nanoclusters: A novel structure at presynaptic terminals

The trans-synaptic cell adhesion molecule neurexin regulates synaptic functions but its high-resolution subcellular localization and dynamics were unknown. Trotter et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201812076) describe previously unrecognized nanoscale clusters of neurexin-1 in...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Daichi, Gotoh, Yukiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683738/
https://www.ncbi.nlm.nih.gov/pubmed/31332023
http://dx.doi.org/10.1083/jcb.201907074
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author Kawaguchi, Daichi
Gotoh, Yukiko
author_facet Kawaguchi, Daichi
Gotoh, Yukiko
author_sort Kawaguchi, Daichi
collection PubMed
description The trans-synaptic cell adhesion molecule neurexin regulates synaptic functions but its high-resolution subcellular localization and dynamics were unknown. Trotter et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201812076) describe previously unrecognized nanoscale clusters of neurexin-1 in presynaptic terminals and their regulation by ADAM10-mediated proteolysis.
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spelling pubmed-66837382020-02-05 Neurexin nanoclusters: A novel structure at presynaptic terminals Kawaguchi, Daichi Gotoh, Yukiko J Cell Biol Commentaries The trans-synaptic cell adhesion molecule neurexin regulates synaptic functions but its high-resolution subcellular localization and dynamics were unknown. Trotter et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201812076) describe previously unrecognized nanoscale clusters of neurexin-1 in presynaptic terminals and their regulation by ADAM10-mediated proteolysis. Rockefeller University Press 2019-08-05 2019-07-22 /pmc/articles/PMC6683738/ /pubmed/31332023 http://dx.doi.org/10.1083/jcb.201907074 Text en © 2019 Kawaguchi and Gotoh http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Kawaguchi, Daichi
Gotoh, Yukiko
Neurexin nanoclusters: A novel structure at presynaptic terminals
title Neurexin nanoclusters: A novel structure at presynaptic terminals
title_full Neurexin nanoclusters: A novel structure at presynaptic terminals
title_fullStr Neurexin nanoclusters: A novel structure at presynaptic terminals
title_full_unstemmed Neurexin nanoclusters: A novel structure at presynaptic terminals
title_short Neurexin nanoclusters: A novel structure at presynaptic terminals
title_sort neurexin nanoclusters: a novel structure at presynaptic terminals
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683738/
https://www.ncbi.nlm.nih.gov/pubmed/31332023
http://dx.doi.org/10.1083/jcb.201907074
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AT gotohyukiko neurexinnanoclustersanovelstructureatpresynapticterminals

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