Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

Lipid droplets (LDs) are neutral lipid storage organelles that transfer lipids to various organelles including peroxisomes. Here, we show that the hereditary spastic paraplegia protein M1 Spastin, a membrane-bound AAA ATPase found on LDs, coordinates fatty acid (FA) trafficking from LDs to peroxisom...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Lun, Weigel, Aubrey V., Ioannou, Maria S., Pasolli, H. Amalia, Xu, C. Shan, Peale, David R., Shtengel, Gleb, Freeman, Melanie, Hess, Harald F., Blackstone, Craig, Lippincott-Schwartz, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683741/
https://www.ncbi.nlm.nih.gov/pubmed/31227594
http://dx.doi.org/10.1083/jcb.201902061

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