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Filamin A mediates isotropic distribution of applied force across the actin network
Cell sensing of externally applied mechanical strain through integrin-mediated adhesions is critical in development and physiology of muscle, lung, tendon, and arteries, among others. We examined the effects of strain on force transmission through the essential cytoskeletal linker talin. Using a flu...
Autores principales: | Kumar, Abhishek, Shutova, Maria S., Tanaka, Keiichiro, Iwamoto, Daniel V., Calderwood, David A., Svitkina, Tatyana M., Schwartz, Martin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683746/ https://www.ncbi.nlm.nih.gov/pubmed/31315944 http://dx.doi.org/10.1083/jcb.201901086 |
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