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High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding

Genetic screens using high-throughput fluorescent microscopes have generated large datasets, contributing many cell biological insights. Such approaches cannot tackle questions requiring knowledge of ultrastructure below the resolution limit of fluorescent microscopy. Electron microscopy (EM) reveal...

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Detalles Bibliográficos
Autores principales: Bykov, Yury S., Cohen, Nir, Gabrielli, Natalia, Manenschijn, Hetty, Welsch, Sonja, Chlanda, Petr, Kukulski, Wanda, Patil, Kiran R., Schuldiner, Maya, Briggs, John A.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683748/
https://www.ncbi.nlm.nih.gov/pubmed/31289126
http://dx.doi.org/10.1083/jcb.201812081