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High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding
Genetic screens using high-throughput fluorescent microscopes have generated large datasets, contributing many cell biological insights. Such approaches cannot tackle questions requiring knowledge of ultrastructure below the resolution limit of fluorescent microscopy. Electron microscopy (EM) reveal...
Autores principales: | Bykov, Yury S., Cohen, Nir, Gabrielli, Natalia, Manenschijn, Hetty, Welsch, Sonja, Chlanda, Petr, Kukulski, Wanda, Patil, Kiran R., Schuldiner, Maya, Briggs, John A.G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683748/ https://www.ncbi.nlm.nih.gov/pubmed/31289126 http://dx.doi.org/10.1083/jcb.201812081 |
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