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The Fusion Oncogene FUS-CHOP Drives Sarcomagenesis of High-Grade Spindle Cell Sarcomas in Mice

Myxoid liposarcoma is a malignant soft tissue sarcoma characterized by a pathognomonic t(12;16)(q13;p11) translocation that produces a fusion oncoprotein, FUS-CHOP. This cancer is remarkably sensitive to radiotherapy and exhibits a unique pattern of extrapulmonary metastasis. Here, we report the gen...

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Detalles Bibliográficos
Autores principales:	Chen, Mark, Xu, Eric S., Leisenring, Nathan H., Cardona, Diana M., Luo, Lixia, Ma, Yan, Ventura, Andrea, Kirsch, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683777/ https://www.ncbi.nlm.nih.gov/pubmed/31427882 http://dx.doi.org/10.1155/2019/1340261

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