Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group

It is increasingly common in oncology practice to perform tumour sequencing using large cancer panels. For pathogenic sequence variants in cancer susceptibility genes identified on tumour-only sequencing, it is often unclear whether they are of somatic or constitutional (germline) origin. There is w...

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Detalles Bibliográficos
Autores principales: Mandelker, D, Donoghue, M, Talukdar, S, Bandlamudi, C, Srinivasan, P, Vivek, M, Jezdic, S, Hanson, H, Snape, K, Kulkarni, A, Hawkes, L, Douillard, J -Y, Wallace, S E, Rial-Sebbag, E, Meric-Bersntam, F, George, A, Chubb, D, Loveday, C, Ladanyi, M, Berger, M F, Taylor, B S, Turnbull, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Special Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683854/
https://www.ncbi.nlm.nih.gov/pubmed/31050713
http://dx.doi.org/10.1093/annonc/mdz136

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